Technical Advantage:  Effective against Gram-positive and – negative Bacteria, and fungi including yeast This is a combination of penicillin, streptomycin and Amphotericin formulated to contain 10,000 units/ml penicillin G, 10 mg/ml streptomycin sulfate and 25 µg/ml amphotericin B.  Penicillin acts by inhibiting bacterial cell-wall synthesis, Streptomycin inhibits prokaryote protein synthesis, and Amphotericin B interferes with fungal membrane permeability.  This combination is effective against Gram-negative and Gram-positive bacteria, fungi and yeasts.  The form provided by Mediatech is solubilized in a proprietary citrate buffer and is recommended for use in cell culture applications at 10 ml/L.