ANA HEp-2 plus

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ANA HEp-2 plus is used for the qualitative and semi-quantitative
determination of antibodies to nuclear and cytoplasmic antigens in
human serum.

Systemic autoimmune diseases such as systemic lupus erythematosus
(SLE), progressive systemic sclerosis (PSS), rheumatoid arthritis (RA),
Sjögren’s syndrome, dermatomyositis, and mixed connective tissue
disease (MCTD) are characterized by the appearance of a variety of
autoantibodies directed against components of the cell nucleus.
Although significance and pathological relevance of some autoantibodies are not completely revealed yet, the detection of autoantibodies is widely established and plays an important role in the
diagnosis of systemic autoimmune diseases (1, 2).


• Slides coated with HEp-2 cells
• Screening test to support for the diagnosis of systemic autoimmune diseases
• Qualitative and semi-quantitative determination of the IgG antibody activity
• Ready-to-use reagents (exception: PBS buffer)
• Quality assured handling in routine laboratories
• Short incubation times (30 min / 30 min) at room temperature
• Consistent processing for the parallel use of multiple IF assays
• High diagnostic sensitivity and specificity
• CE marked

Generic Assay

Medipan GmbH GA

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